¾Ï ¿¬±¸ Common Data Element¿¡ ±â¹ÝÇÑ Microarray Gene Expression-Object Model°ú Clinical Document ArchitectureÀÇ ¿¬µ¿

¹ÚÀ¯¶û1), ¹ÚÁö¿¬1), ±è¼¼¿µ1), ¼­È­Á¤1), ÀÌÁ¤¾Ö1), ±èÁÖÇÑ*1)

1)¼­¿ï´ëÇб³ ÀÇ°ú´ëÇÐ »ý¸íÀÇ·áÁ¤º¸ÇÐ

Abstract : Microarray is capable of profiling gene expression patterns of tens of thousands of genes in single experiment. To assess the relevance of microarray analysis it is required to combine clinical and genomics information. In order to meet the growing need for improved data communication between clinical and microarray data, it is necessary to overcome the barriers of data heterogeneity and lack of standards. The MAGE-OM (Microarray Gene Expression Object Model) is a data exchange model, which attempts to define standard objects for gene expression. MAGE-OM, however, cannot provide a model for the clinical data of source. HL7's CDA (Clinical Document Architecture) is the document model for exchange of clinical information using XML. In this study, we show NCICB (National Cancer Institute Center for Bioinformatics) CDE (Common Data Element) based CDA template modeling for integration of MAGE-OM and CDA. First, we extract data elements in clinical data from 118 lung cancer sources. Second, we develop the structured model using these elements based on the CDE. Third, we link MAGE-OM to CDA using a BioSource class, which describes the original biomaterial in the MAGE-OM. Although there still remain technical and organizational issues to be solved, this is a promising method in order to represent a source's clinical data in standard structured format like CDA.
keyword : MAGE-OM, CDA, CDE, CDA Template modeling

¿¬Á¦ºÐ·ù

,


÷ºÎÇÑ ÆÄÀÏ

kosmi04_parkyurang.hwp

÷ºÎÇÑ e-posterÆÄÀÏ

Åõ°í³»¿ëÀ» »èÁ¦ÇϽ÷Á¸é "»èÁ¦"¹öÆ°À» ´©¸£½Ã°í ´Ù½Ã Á¢¼öÇÏ¿© Áֽñ⠹ٶø´Ï´Ù.

 ¾Ï È£

´ëÇÑÀÇ·áÁ¤º¸ÇÐȸ
Copyright (c) 2002 by The Korean Society of Medical Informatics