신독성약물 과처방 분석: 2개월간의 병원처방정보 분석 결과

최지은1), 이영호2), 강운구2), 차가을1), 서영준1), 이경진3), 황성철3), 박래웅*1)3)

1)아주대학교병원 지역임상시험센타
2)가천의과학대학
3)아주대학교 의과대학 의료정보학과

Abstract : The nephrotoxic drug dose adjustment is essential for patient safety, but dose adjustments are sometimes skipped or ignored. This is a retrospective study to evaluate the appropriateness of physicians', especially residents', prescribing behavior. We retrospectively analyzed the two-months OCS data of physicians' prescriptions in a tertiary teaching hospital. on the basis of adjusted dose to renal function. Surprisingly, 8 of the 158 doctors (5.1%) wrote 245 of the 481 overdose orders (51%). The recommended dose was more than doubled in 67% of the total overdoses (366 of 481 overdoses). This study found that a small fraction of doctors caused most of the overdoses.
keyword : nephrotoxic drugs, prescription, overdosage, renal function, medication error

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